Tissue immunostaining for factor XIIIa in dermal dendrocytes of pityriasis alba skin lesions

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Tissue immunostaining for factor XIIIa in dermal dendrocytes of pityriasis alba skin lesions*

BACKGROUND Pityriasis alba affects 1% of the world population and about 9.9% of the children in Brazil. However, its etiology remains uncertain. OBJECTIVE The objective of the present study was to evaluate the immunoexpression of factor XIIIa in dermal dendrocytes of skin lesions of pityriasis alba. METHOD Twenty patients with pityriasis alba and 20 patients with atopic dermatitis underwent...

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391 Letters to the Editor Sir, Human papillomaviruses (HPVs) are double-stranded DNA virus with over 100 different identified types. The virus mainly infects the cutaneous and mucosal squa-mous stratified epithelia of the anogenital region. HPV replication is linked to the differentiation and maturation of squamous cells, followed by terminal differentiation, with hyperplasia associated with th...

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Oral submucosal dendrocytes: factor XIIIa+ and CD34+ dendritic cell populations in normal tissue and fibrovascular lesions.

Factor XIIIa+ and CD34+ dendritic cells, believed to be subsets of monocyte/macrophages, have been identified in dermis and in dermal tumors. The purpose of this study was to determine the presence and distribution of analogous cell types in oral submucosa and oral fibro-vascular lesions. Antibodies to XIIIa, CD34, S-100 protein, and macrophage antigen (MAC 387) were tested on formalin-fixed, p...

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Molecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review).

The human dermis contains a series of dendritic cells which express different phenotypes including Factor XIIIa immunoreactivity. This compound is related to a blood coagulation factor participating in angiogenesis, in the final stages of the clotting cascade and in wound healing. In normal skin, Factor XIIIa is expressed in specific dermal dendrocytes (DD) derived from the monocyte/macrophage ...

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Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin.

The immunocytochemical identification and characterization of indigenous dermal dendritic cells (dermal dendrocytes) using a rabbit polyclonal antibody to clotting enzyme factor XIII subunit A (FXIIIa) was carried out on normal and inflamed human cutaneous tissue. The immunophenotype of FXIIIa positive dendritic cells was analysed with a panel of 18 monoclonal antibodies using immunoperoxidase ...

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ژورنال

عنوان ژورنال: Anais Brasileiros de Dermatologia

سال: 2014

ISSN: 0365-0596

DOI: 10.1590/abd1806-4841.20142201